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Sundar Raj, M.
- Nanocomposites Based on Polymer and Hydroxyapatite for Drug Delivery Application
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Authors
Affiliations
1 Biomedical Engineering, Bharath University, Chennai - 600 073, IN
2 R & D Engineer, URILAB Systems-Diagnostics, New Delhi- 110 081
3 Department of ECE, PSNACET, Dindigul – 624 622
4 SMK Fomra Institute of Technology, Chennai – 600 103
1 Biomedical Engineering, Bharath University, Chennai - 600 073, IN
2 R & D Engineer, URILAB Systems-Diagnostics, New Delhi- 110 081
3 Department of ECE, PSNACET, Dindigul – 624 622
4 SMK Fomra Institute of Technology, Chennai – 600 103
Source
Indian Journal of Science and Technology, Vol 6, No S5 (2013), Pagination: 4653-4658Abstract
This research paper tells about sustained delivery of small molecular drug ciprofloxacin using hydroxyapatite hybrid poly (vinyl alcohol) nanocomposites. Hydroxyapatite - poly (vinyl alcohol) nanocomposites are used as a vehicle to carry drug, protein, implantable materials etc. In situ synthesized hydroxyapatite hybrid poly (vinyl alcohol) matrix was characterized using different characterization techniques like XRD, SEM and FTIR. Small molecular drug ciprofloxacin was loaded into hydroxyapatite hybrid poly (vinyl alcohol) nanocomposites. The morphology of drug free and drug loaded hydroxyapatite concoction poly (vinyl alcohol) nanocomposites is observed using SEM. In-vitro drug release is quantified using UV/VIS spectrophotometer.Keywords
Hydroxyapatite (HAP), Poly (Vinyl Alcohol) (PVA), Ciprofloxacin, Nanocomposites, Sustained Release, Drug Delivery, X-ray Diffraction (XRD), Scanning Electron Microscope (SEM)References
- Wang X, Hui A et al. (2010). Towards sustained delivery of small molecular drugs using hydroxyapatite microsphere as the vehicle, Advance Power Technology, vol 21(3), 268–272.
- Wahl D A, and Czernuszka J T (2006). Collagen hydroxyapatite composites for hard tissue repair, European Cells and Materials, vol 11, 43–56.
- Degirmembasi N, Kalyon D M et al. (2006). Biocomposites of nanohdyroxyaaptite will collegen, and poly (vinyl alcohol), Colloids and Surfaces B: Biointerfaces, vol 48(1), 42–49.
- Asron A S, Henning S et al. (2010). Poly vinyl alcohol collegen hydroxyapatite biocomposites, nano fibrous scaffold: mimicking the key feature of natural bone at the nanoscale level, Polymer, vol 51(4), 868–876.
- Taguchi T, Kishida A et al. (1998). Hydroxyapatite formation on/in poly(vinyl alcohol) hydrogel matrices using a novel alternate soaking process, Chemistry Letters, vol 27, No. 8, 711–712.
- Pan Y S, Xiong D S et al. (2007). Friction characteristics of poly (vinyl alcohol) hydrogel as an articular cartilage biomaterial, Key Engineering Materials, vol 330–332, 1297–1300.
- Noguchi T, Yamamuro T et al. (1991). Poly (vinyl alcohol) hydrogel as an artificial articular cartilage: evaluation of biocompatibility, Journal of Applied Biomaterials, vol 2(2), 101–107.
- Paul W, and Sharma C P (2003). Ceramic drug delivery: a perspective, Journal of Biomaterials Application, vol 17(4), 253.
- Paul W, and Sharma C P (2006). Nanoceramic materials: Biomedical applications, American Journal of Biochemistry & Biotechnology, vol 2, 41–48.
- Barroug A, and Glimche M (2002). Hydroxyapatite crystals as a local delivery system for cisplatin: adsorption and release of cisplatin in vitro. Journal of orthopaedics, vol 20(2), 274–280.
- Chow A W, Hall C B et al. (1992). General guidelines for the evaluation of new anti-infective drugs for the treatment of respiratory tract infections, Clinical Infectious Diseases, vol 15(Supplement 1), S62–S88.
- Mylotte J M, Ksiazek S et al. (1994). Bentley Rational approach to the antibiotic treatment of pneumonia in elderly, Drug & Aging, vol 4(1), 21–33.
- Cunha B A (1995). The antibiotic treatment of community- acquired, athipical, and nosocomial pneumonias, The Medical clinics of North America, vol 79(3), 581–597.
- Vogel F (1995). A guide to the treatment of lower respiratory tract infections, Drugs, vol 50(1), 62–72.
- Ortqvist A (1995). Antibiotic treatment of community-acquired pneumonia in clinical practice: a European perspective, Journal of Antimicrobial Chemotherapy, vol 35(1), 205–212.
- Lambert H P, and O’Grady F W (1992). Antibiotic and Chemotherapy, 6th Edn., Churchill Livingstone, Edinburgh, 245–262.
- Armstrong E P, Elsberry V A (1997). Bone and joint infections, Dipiro J T, Talbert R L, Yee G C, Matzke G R, Wells B G, Posey L M (Eds.), Pharmacotherapy. A Pathophysiologic Approach, 3rd Edn, Appleton & Lange, Stamford, 2221–2235.
- Gupta S, Nayar S et al. (2008). Effect of particle morphology on drug release from poly (vinyl alcohol)- hydroxyapatite nanocomposites, Kapecele J. Soluble biomedical polymers, polim med vol 7(3), 191–221.
- Shiffman M L, and Keith F B (1990). Pathogenesis of ceftriaxone –associated biliary sludge, In vitro studies of calcium – ceftriaxone binding and solubility, Gastroenterology, vol 99(6), 1772–1778.
- Person Identification for Visually Impaired using LabVIEW
Abstract Views :156 |
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Authors
Affiliations
1 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN
1 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN
Source
Indian Journal of Science and Technology, Vol 8, No 31 (2015), Pagination:Abstract
Visually impaired find difficult to identify colors and person, the main objective of this project is to make them overcome these. An external camera is fitted with goggles for acquiring images. The acquired image is processed to obtain the required features such as colors in the case of audio colors or facial features in the case of personal identification. The obtained feature is encoded using MATLAB, then fed into LabVIEW through which speakers are connected to get the respective audio signals. The color presented to the camera is converted to corresponding sound. This will also be useful for the visually impaired to identify their friends and foes using face identification software which is implemented in here. This project is meant to describe light, by its frequency and intensity, in terms of an audible signal. However, the domain of the system here is limited only to primary and secondary colors. The complete software solution is implemented using LabVIEW and MATLAB.Keywords
Audio Colors, LabVIEW, Person Recognition, MATLAB- Study of Enzyme Kinetics using Capacitive Biosensor-An Alternate to Colorimeter
Abstract Views :182 |
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Authors
Affiliations
1 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN
1 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN
Source
Indian Journal of Science and Technology, Vol 8, No 31 (2015), Pagination:Abstract
A novel sensor approach based on measurement of changes in capacitance of an electrochemical cell produced during enzyme catalyzed formation of products is described. The electrochemical property such as capacitance of an electrolyte between electrochemical cell depends on its ionic compositions, in turn depends on the resulting ionic constituents caused by catalytic action of the enzyme. Generation of micromolar (μM) concentration of ionic species causes large changes in capacitance that is measurable in picofarad (pF) range in capacitive electrodes. Broad clinical analytical application of this technique is demonstrated in this report by application to diagnostically valued enzymes measurements like pyrophosphatases and phosphatases. Specific measurements of enzyme activities were achieved over the concentration range of 0.125 – 5.0 mM of respective substrates. The performance of the electrochemical sensor based enzyme biochemical assays were compared directly with identical assays employing spectrophotometric detection and found to match well.Keywords
Capacitance Changes, Electrochemical Cell, Enzyme Kinetics, Shigella Apyrase- Ridgelet based Feature Extraction for Breast Cancer Detection using Ultrasound Images
Abstract Views :167 |
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Authors
Affiliations
1 Department of Biomedical Engineering, Jerusalem College of Engineering, Chennai - 600100, Tamil Nadu, IN
2 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN
1 Department of Biomedical Engineering, Jerusalem College of Engineering, Chennai - 600100, Tamil Nadu, IN
2 Department of Biomedical Engineering, Bharath University, Chennai - 600073, Tamil Nadu, IN